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Cardiac Power Output (CPO) is a single hemodynamic parameter that integrates both pressure and flow components of cardiac performance: CPO = (Mean Arterial Pressure × Cardiac Output) / 451 (in Watts). CPO is the strongest hemodynamic predictor of in-hospital mortality in cardiogenic shock and acute myocardial infarction complicated by cardiogenic shock. Derived from right heart catheterization data, CPO < 0.6 W identifies patients at highest mortality risk and is a threshold commonly used to guide mechanical circulatory support (MCS) escalation decisions. The cardiac power index (CPI = CPO / BSA) normalizes for body size.
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