CIRC Score — COVID-19 ICU Risk Calculator

The COVID-19 ICU Risk Calculator (CIRC) is an early prediction model developed from U.S. multicenter hospitalized COVID-19 patient data to identify patients at highest risk of requiring ICU-level care (mechanical ventilation, vasopressors, or ICU escalation) during hospitalization. CIRC uses 7 variables available at initial presentation: age, sex, BMI, SpO₂ on room air, comorbidity burden, C-reactive protein (CRP), and D-dimer. It was designed for early in-hospital triage to allocate ICU resources and identify patients who may benefit from early aggressive interventions.