COVID-GRAM — COVID-19 Gram Critical Illness Risk Score

The COVID-GRAM (COVID-19 Gram Risk Assessment Model) is a validated scoring tool derived from a large Chinese multicenter cohort (> 1,500 COVID-19 patients from 575 hospitals) to predict the probability of critical illness (composite: ICU admission, invasive mechanical ventilation, or death) in hospitalized COVID-19 patients. COVID-GRAM incorporates 10 variables identified through LASSO regression and multivariate logistic regression. A web-based calculator providing percentage risk outputs was made widely available during the early pandemic and gained international adoption.