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The Estimated Average Glucose (eAG) from HbA1c is a validated conversion that translates HbA1c percentage into a real-world average blood glucose value in mg/dL or mmol/L that patients can relate to their daily glucometer readings. The formula is derived from the ADAG (A1c-Derived Average Glucose) study, which enrolled 507 subjects with T1DM, T2DM, and no diabetes and correlated continuous glucose monitoring (CGM) readings with simultaneous HbA1c measurements: eAG (mg/dL) = (28.7 × HbA1c) − 46.7. This conversion helps bridge the gap between laboratory HbA1c values and the daily glucose experience of patients with diabetes, supporting patient education and glycemic management.
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