Framingham Coronary Heart Disease Risk Score (10-Year)

The Framingham Coronary Heart Disease (CHD) Risk Score is the original landmark 10-year cardiovascular risk prediction model derived from the Framingham Heart Study — a prospective longitudinal cohort study of cardiovascular disease since 1948. The sex-specific Framingham CHD Risk Score (D'Agostino 2008 update) integrates traditional cardiovascular risk factors (age, total cholesterol, HDL cholesterol, systolic blood pressure, blood pressure treatment status, diabetes, and smoking status) to estimate 10-year probability of a first cardiovascular event (MI, coronary death, angina, coronary insufficiency, stroke, TIA, or peripheral arterial disease). The Framingham CHD score laid the conceptual foundation for all subsequent global CV risk prediction models (ASCVD Pooled Cohort Equations, SCORE, QRISK).