HCM Risk-SCD — Hypertrophic Cardiomyopathy Sudden Death Risk Calculator

The HCM Risk-SCD is the 2014 European Society of Cardiology (ESC) validated prediction model for estimating 5-year risk of sudden cardiac death (SCD) in adults with hypertrophic cardiomyopathy (HCM). The model integrates 7 clinical and imaging predictors into a continuous mathematical equation that generates a 5-year SCD probability, enabling evidence-based ICD implantation decisions. Unlike older binary 'minor/major risk factor' classification systems, HCM Risk-SCD provides a continuous probability estimate, capturing more nuanced risk gradients. The model was derived from the HCM European Registry (3675 patients) and validated externally, and its use is endorsed in 2014 ESC and 2020 ACC/AHA HCM guidelines.