H — Hepatic or Renal Disease

No hepatic or renal disease+0Hepatic or renal disease (+1 pt)+1

E — Ethanol (Alcohol) Abuse

No alcohol abuse+0Alcohol abuse (+1 pt)+1

M — Active Malignancy

No active malignancy+0Active malignancy (+1 pt)+1

O — Older Age (> 75 Years)

Age ≤ 75 years+0Age > 75 years (+1 pt)+1

R — Reduced Platelet Count or Function

Normal platelet count and function+0Reduced platelets or platelet dysfunction (+1 pt)+1

R₂ — Re-Bleeding Risk (Prior Bleeding on Anticoagulation)

No prior bleeding on anticoagulation+0Prior major bleeding on anticoagulation (+2 pts)+2

H — Uncontrolled Hypertension

BP controlled or no hypertension+0Uncontrolled hypertension (+1 pt)+1

A — Anemia

No anemia+0Anemia present (+1 pt)+1

G — Genetic Factors (CYP2C9 Variant for Warfarin Users)

Unknown or normal CYP2C9 / on DOAC (not warfarin)+0CYP2C9 variant on warfarin (+1 pt)+1

E — Excessive Fall Risk

No excessive fall risk+0Excessive fall risk (+1 pt)+1

S — Stroke History

No prior stroke+0Prior stroke (+1 pt)+1

HEMORR₂HAGES Bleeding Risk Score