IMPACT Score — Traumatic Brain Injury Outcome Predictor

The International Mission for Prognosis and Analysis of Clinical Trials in TBI (IMPACT) Score is a validated prognostic model predicting 6-month unfavorable functional outcome (Glasgow Outcome Scale Extended — GOSE ≤ 4, which corresponds to severe disability, vegetative state, or death) after moderate-to-severe traumatic brain injury (TBI). Three IMPACT models exist: Core (4 variables), Extended (+ CT findings), and Lab (+ laboratory values). IMPACT was derived from 11 international TBI clinical trials and observational studies (n > 8,000) and is among the strongest TBI prognostic tools available.