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The Mehran Score is a validated 8-variable risk scoring system for predicting contrast-induced acute kidney injury (CI-AKI), defined as an increase in serum creatinine ≥0.5 mg/dL or ≥25% above baseline within 48–72 hours of iodinated contrast administration. Developed by Mehran et al. (2004) from a large percutaneous coronary intervention (PCI) database, the score quantifies pre-procedural risk to guide prophylactic strategies (IV hydration, N-acetylcysteine, contrast dose minimization) and to identify patients at highest risk for dialysis or prolonged hospitalization.
Hypotension (SBP < 80 mmHg for ≥1 Hour Requiring IABP or Vasopressors Within 24h of Contrast)
Intra-Aortic Balloon Pump (IABP) Use
Congestive Heart Failure (NYHA Class III–IV and/or History of Pulmonary Edema)
Age
Anemia (Baseline Hematocrit < 39% in Men or < 36% in Women)
Diabetes Mellitus
Contrast Agent Volume
Renal Function (Serum Creatinine or eGFR)
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