NCCN-IPI — National Comprehensive Cancer Network International Prognostic Index for DLBCL

An enhanced prognostic score for diffuse large B-cell lymphoma (DLBCL) that improves upon the standard IPI by using age cutoffs (41–60, 61–75, > 75), distinguishing LDH levels (≥ 1–3× ULN vs. > 3× ULN), and including specific high-risk extranodal involvement. Derived from R-CHOP treated cohorts to better discriminate survival outcomes.