Respiratory Domain

0 — SpO₂/FiO₂ ≥ 292 or PF ratio ≥ 400 (normal)+01 — SpO₂/FiO₂ 220–291 or IMV with PF < 400 (+1 pt)+12 — SpO₂/FiO₂ < 220 on any oxygen or IMV (+2 pts)+23 — SpO₂/FiO₂ < 148 on at least 0.5 FiO₂ or IMV with PF < 100 (+3 pts)+3

Cardiovascular Domain

0 — No vasoactives, lactate < 5, pH ≥ 7.0 (normal)+01 — Lactate 5–10.9 mmol/L OR MAP < normal for age (+1 pt)+12 — 1 vasoactive (dopamine, dobutamine, epinephrine, norepinephrine, milrinone, vasopressin) (+2 pts)+23 — Lactate ≥ 11 mmol/L OR pH < 7.0 OR ≥ 2 vasoactives (+3 pts)+3

Coagulation Domain

0 — No coagulation abnormalities (normal)+01 — Platelets 100–149 × 10⁹/L OR INR 1.5–1.9 OR fibrinogen 100–199 mg/dL (+1 pt)+12 — Platelets 50–99 × 10⁹/L OR INR 2.0–10.0 OR fibrinogen < 100 mg/dL OR D-dimer ≥ 8 × ULN (+2 pts)+23 — Platelets < 50 × 10⁹/L OR INR > 10 (+3 pts)+3

Neurological Domain

0 — GCS 15 and bilateral equal pupils (normal)+01 — GCS 11–14 (+1 pt)+12 — GCS 5–10 (+2 pts)+23 — GCS 3–4 OR fixed dilated pupils (+3 pts)+3

Phoenix Sepsis Score for Pediatric Sepsis

Phoenix Sepsis Score for Pediatric Sepsis