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The PHQ-2 is an ultra-brief 2-item validated screening tool for major depressive disorder (MDD), derived from the longer PHQ-9. It asks about the two core symptoms of depression — anhedonia and depressed mood — over the past 2 weeks. Each item is scored 0–3, yielding a total score of 0–6. A PHQ-2 score ≥ 3 is the validated cutoff for a positive depression screen, prompting follow-up with the full PHQ-9. The PHQ-2 has sensitivity of 83% and specificity of 92% for MDD.
Q1: Over the last 2 weeks, how often have you been bothered by little interest or pleasure in doing things?
Q2: Over the last 2 weeks, how often have you been bothered by feeling down, depressed, or hopeless?
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