Predicts the risk of Symptomatic Intracerebral Hemorrhage (sICH) in ischemic stroke patients receiving IV thrombolysis (tPA), to guide shared decision-making regarding thrombolytic therapy.

Parameters

S — Sugar (Serum Glucose at Admission)

< 8.0 mmol/L (< 144 mg/dL)+0≥ 8.0 mmol/L (≥ 144 mg/dL) — hyperglycemia+1

E — Early Infarct Signs on NCCT

Absent — normal initial CT or minimal changes+0Present involving ≤ 1/3 of MCA territory+1Present involving > 1/3 of MCA territory (major established infarct)+2

D — hyperDense Artery Sign on NCCT

Absent+0Present (hyperdense MCA, basilar, or ICA sign)+1

A — Age

< 75 years+0≥ 75 years+1

N — Admission NIHSS Score

0–9 (mild stroke)+010–19 (moderate stroke)+1≥ 20 (severe stroke)+2

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CalculatorsSEDAN Score for Post-tPA Hemorrhage

NeurologyScore

SEDAN Score for Post-tPA Hemorrhage