Shock Severity (SCAI Stage or Vasopressor Requirement)

Hypotension responsive to fluids without vasopressors (SCAI B) — 0 pts+0Vasopressor requirement to maintain MAP ≥ 65 (SCAI C) (+1 pt)+1Multi-vasopressor or escalating high-dose vasopressors (SCAI D–E) (+2 pts)+2

End-Organ Hypoperfusion Markers

Lactate < 2 mmol/L and no end-organ injury (0 pts)+0Lactate 2–4 mmol/L or oliguria or creatinine rising (+1 pt)+1Lactate > 4 mmol/L or anuria or severe multiorgan failure (+2 pts)+2

Prior Cardiac Arrest (before or during current hospitalization)

No prior cardiac arrest (0 pts)+0Prior resuscitated cardiac arrest (+2 pts)+2

Age ≥ 75 or Multiple Major Comorbidities (DM, CKD, COPD, prior MI)

Age < 75, no or minimal comorbidities (0 pts)+0Age 65–74 or 1–2 comorbidities (+1 pt)+1Age ≥ 75 or ≥ 3 comorbidities (+2 pts)+2

Need for Mechanical Circulatory Support (IABP, Impella, or ECMO already in use or immediately needed)

No MCS needed or IABP only (0 pts)+0Impella or escalation from IABP needed (+1 pt)+1VA-ECMO needed or ongoing ECMO (+2 pts)+2

SEX-SHOCK Score — Cardiogenic Shock In-Hospital Mortality Prediction

SEX-SHOCK Score — Cardiogenic Shock In-Hospital Mortality Prediction