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Identifies patients with Staphylococcus aureus bacteremia (SAB) at high risk for infective endocarditis (IE). VIRSTA was derived to help clinicians determine which patients with SAB require urgent transthoracic or transesophageal echocardiogram (TTE/TEE) for IE evaluation, as routine echocardiography of all SAB patients is resource-intensive.
Community-Acquired SAB (as opposed to healthcare-associated or nosocomial)
History of Infective Endocarditis
Prosthetic Heart Valve or Cardiac Device (CIED)
Persistent Bacteremia (> 48 hours after source control)
Known Injection Drug Use (IDU)
Vertebral Osteomyelitis (clinically or radiologically suspected)
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