DUPIXENT is administered by subcutaneous injection. Atopic Dermatitis
General dosing
Dosage in Adults : Recommended dosage is an initial dose of 600 mg (two 300 mg injections), followed by 300 mg given every 2 weeks (Q2W).
General dosing
Dosage in Adult and Pediatric Patients 12 Years and Older : Initial Loading Dose Subsequent Dosage 400 mg (two 200 mg injections) 200 mg every 2 weeks (Q2W) Or 600 mg (two 300 mg injections) 300 mg every 2 weeks (Q2W) Dosage for patients with oral corticosteroid-dependent asthma or with co-morbid moderate-to-severe atopic dermatitis or adults with co-morbid chronic rhinosinusitis with nasal polyps 600 mg (two 300 mg injections) 300 mg every 2 weeks (Q2W)
General dosing
Recommended dosage for adult and pediatric patients 12 years of age and older is 300 mg given every 2 weeks (Q2W). Eosinophilic Esophagitis : Body Weight
General dosing
Recommended Dosage in Adult and Pediatric Patients 1 Year and Older, Weighing At Least 15 kg 15 to less than 30 kg 200 mg every 2 weeks (Q2W) 30 to less than 40 kg 300 mg every 2 weeks (Q2W) 40 kg or more 300 mg every week (QW) Prurigo Nodularis :
General dosing
Recommended dosage for adult patients is an initial dose of 600 mg (two 300 mg injections), followed by 300 mg given every 2 weeks (Q2W). Chronic Obstructive Pulmonary Disease :
General dosing
Recommended dosage for adult patients is 300 mg given every 2 weeks (Q2W). Chronic Spontaneous Urticaria
Pediatric Dosing
General dosing
Dosage in Pediatric Patients 6 Months to 5 Years of Age : Body Weight Initial and Subsequent Dosage 5 to less than 15 kg 200 mg (one 200 mg injection) every 4 weeks (Q4W) 15 to less than 30 kg 300 mg (one 300 mg injection) every 4 weeks (Q4W)
General dosing
Dosage in Pediatric Patients 6 Years of Age and Older : Body Weight Initial Loading Dose Subsequent Dosage Q2W – every 2 weeks; Q4W – every 4 weeks 15 to less than 30 kg 600 mg (two 300 mg injections) 300 mg Q4W 30 to less than 60 kg 400 mg (two 200 mg injections) 200 mg Q2W 60 kg or more 600 mg (two 300 mg injections) 300 mg Q2W Asthma
General dosing
Dosage in Pediatric Patients 6 to 11 Years of Age : Body Weight Initial Dose and Subsequent Dosage 15 to less than 30 kg 300 mg every 4 weeks (Q4W) ≥30 kg 200 mg every 2 weeks (Q2W) For pediatric patients 6 to 11 years old with asthma and co-morbid moderate-to-severe atopic dermatitis, follow the recommended dosage as per Table 2 which includes an initial loading dose. Chronic Rhinosinusitis with Nasal Polyps :
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