Rufinamide

BANZEL should be given with food. Tablets can be administered whole, as half tablets, or crushed Measure oral suspension using provided adapter and dosing syringe Pediatric patients 1 year and older: Starting daily dose: 10 mg/kg per day in two equally divided doses Increase by 10 mg/kg increments every other day to maximum dose of 45 mg/kg per day, not to exceed 3200 mg per day, in two divided doses Adults: Starting daily dose: 400-800 mg per day in two equally divided doses Increase by 400-800 mg every other day until a maximum dose of 3200 mg per day, in two divided doses, is reached 2.1 Dosage Information Pediatric patients ( 1 year to less than 17 years) The recommended starting daily dose of BANZEL in pediatric patients with Lennox-Gastaut Syndrome is approximately 10 mg/kg administered in two equally divided doses. The dose should be increased by approximately 10 mg/kg increments every other day until a maximum daily dose of 45 mg/kg, not to exceed 3200 mg, administered in two equally divided doses, is reached. It is not known whether doses lower than the target doses are effective.