› ! Lower GI hemorrhage → › ! Diverticulitis → › Hemorrhoids (thrombosed) → › First 5 minutes
› Escalate to resuscitation bay if unstable
› Systolic blood pressure less than 90 mmHg
› Altered mental status
› Monitoring
› Continuous pulse oximetry
› Cardiac monitor
› IV access
› Two large bore peripheral IVs
› IO access if IV failure and unstable
› Initial fluids
› Balanced crystalloid bolus 500 mL to 1 L
› Stop boluses if pulmonary edema signs
› Blood products local protocol dependent
› Activate massive transfusion if ongoing shock
› Early type specific or O negative if delay
Transfusion and hemostasis strategy
› Hemostasis strategy
› Restrictive transfusion target when stable
› Hemoglobin under 70 g/L transfuse typical
› Higher threshold with active ischemia local protocol dependent
› Platelet transfusion thresholds local protocol dependent
› Platelets under 50 x 10^9 per L with active bleeding
› Higher targets for procedures
› Anticoagulant reversal local protocol dependent
› Warfarin
› Vitamin K IV
› PCC dosing per INR
› Dabigatran
› Idarucizumab
› Hemodialysis option in severe renal failure
› Factor Xa inhibitors
› PCC option
› Andexanet availability local protocol dependent
› Diagnostic sequencing
› If unstable and ongoing bleeding
› CT angiography early
› IR consult early
› If stable
› Colonoscopy planning with GI
› Stool studies if colitis features
› If upper GI source possible
› Consider PPI IV
› Early EGD pathway
Therapeutics by suspected cause
› Therapeutics
› Suspected infectious colitis
› Sepsis bundle if shock
› Antibiotics based on syndrome local protocol dependent
› Suspected ischemic colitis
› IV fluids
› Broad spectrum antibiotics if moderate to severe disease local protocol dependent
› Suspected hemorrhoids or fissure
› Topical analgesia local protocol dependent
› Stool softening strategy local protocol dependent
› Reassessment loop
› Vital signs frequency
› Every 5 to 15 minutes if unstable
› Every 30 to 60 minutes if stable
› Bleeding monitoring
› Stool count and appearance
› Ongoing clots
› Repeat labs timing
› Hemoglobin repeat in 4 to 6 hours if ongoing bleeding
› Earlier repeat if deterioration
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