›IV fluids if failed oral trial
›Severe dehydration
›Isotonic crystalloid bolus
›Transition to deficit replacement and maintenance
›ORT dosing
›Mild dehydration replacement
›50 mL/kg over 4 hours local protocol dependent
›Additional for ongoing stool losses
›Moderate dehydration replacement
›100 mL/kg over 4 hours local protocol dependent
›Small frequent volumes every 1 to 2 minutes
›Ongoing losses replacement
›10 mL/kg per loose stool
›2 mL/kg per emesis
›IV fluids dosing
›Initial bolus for shock
›0.9% sodium chloride 20 mL/kg
›Repeat bolus based on perfusion reassessment
›Deficit replacement
›Isotonic fluids preferred
›Avoid hypotonic fluids in acute resuscitation
›Maintenance fluids
›Isotonic maintenance consideration
›Dextrose addition if hypoglycemia risk
›Ondansetron for ORT facilitation
›Single dose strategy
›0.15 mg/kg by mouth
›Maximum 8 mg
›Weight based options
›8 to 15 kg 2 mg by mouth
›15 to 30 kg 4 mg by mouth
›More than 30 kg 8 mg by mouth
Electrolyte correction principles
›Correction safety
›Hypernatremia
›Slow correction to reduce cerebral edema risk
›Frequent sodium checks in severe cases
›Hyponatremia
›Seizure management pathway if symptomatic
›Avoid rapid overcorrection
›Reassessment and response
›Timing
›After each bolus
›Every 30 to 60 minutes during ORT
›Repeat targets
›Heart rate trend
›Capillary refill trend
›Mental status trend
›Urine output trend