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Suspected Deep Vein Thrombosis SymptomsAPPROACH

CHEST AND CARDIOVASCULAR · 19 SECTIONS

⚲

419 items

☷ Legend

⚲

Resuscitation and Universal Approaches9▾

Chest and Cardiovascular12▾

Pacemaker And Icd Related Presentations Acute Limb Ischemia And Leg Pain Suspected Deep Vein Thrombosis Symptoms Hypertension Chest Pain Palpitations And Tachyarrhythmia Symptoms Bradycardia Symptoms Syncope And Presyncope Syncope With Neurologic Concern Unilateral Leg Swelling Bilateral Leg Swelling Calf Pain And Swelling

Respiratory11▾

Abdominal and Gastrointestinal24▾

Renal and Urinary7▾

Neurologic11▾

Back and Neck8▾

Women's Health, Pregnancy, and GU11▾

Infectious Disease and Fever Syndromes11▾

Allergy and Dermatology7▾

Musculoskeletal and Extremities14▾

Trauma and Wounds14▾

ENT, Eye, Dental10▾

Endocrine, Metabolic, and Abnormal Labs9▾

Toxicology and Behavioral14▾

Pediatrics16▾

Environmental and Exposure4▾

01History/hx72

Presenting symptoms

›Symptom profile

›Unilateral leg swelling

›Unilateral calf or thigh pain

›Limb heaviness

›Erythema

›Warmth

›Dilated superficial veins

›Bilateral symptoms

›Asymptomatic

›Symptom context

›Recent surgery

›Recent trauma

›Recent immobilization

›Recent long travel

›Postpartum

›Active cancer treatment

›Prior venous thromboembolism history

OPQRST

›OPQRST framework

›Onset

›Provocation and palliation

›Quality

›Region and radiation

›Severity

›Timing

Onset

›Timing of onset

02Alarm Features/alarm23

Time critical threats

›Immediate escalation triggers

›Hemodynamic instability

›Hypoxemia

›Syncope with PE concern

›Severe respiratory distress

›Massive leg swelling with severe pain

›Threatened limb concern

Vital sign danger thresholds

›High risk vitals

›Systolic blood pressure under 90 mmHg

›Oxygen saturation under 90 percent on room air

›Marked tachycardia

›Persistent tachypnea

High risk exam findings

›Exam red flags

›Cyanotic painful swollen leg

›Severe pain out of proportion

›Tense compartments

›Absent distal pulses

›Rapidly spreading erythema

High risk historical triggers

›Context red flags

›Recent major surgery within 4 weeks

›Postpartum within 6 weeks

›Active cancer with new swelling

›Known thrombophilia with new symptoms

03Medications/meds21

Medication reconciliation

›Current medications

›Anticoagulants

›Antiplatelets

›Hormonal contraception

›Estrogen therapy

›Testosterone therapy

›Erythropoiesis stimulating agents

Anticoagulant details

›Anticoagulant specifics

›Last dose timing

›Adherence concerns

›Recent interruptions

›Drug interactions

Bleeding risk medication classes

›Concomitant bleeding risk

›NSAIDs

›SSRIs and SNRIs

›Systemic steroids

Contraindications to anticoagulation

›High risk contraindications

›Active major bleeding

›Recent intracranial hemorrhage

›Recent major surgery with uncontrolled bleeding risk

›Severe thrombocytopenia

04Diet/diet10

Intake and hydration

›Recent intake pattern

›Poor oral intake

›Dehydration risk

›Recent vomiting or diarrhea

Substance exposures

›Exposures

›Caffeine and energy drinks

›Alcohol exposure

Diet related comorbid triggers

›Pattern factors

›High salt intake with baseline edema

›Low protein intake with hypoalbuminemia risk

05Review of Systems/ros19

Cardiopulmonary

›PE related symptoms

›Dyspnea

›Pleuritic chest pain

›Cough

›Hemoptysis

›Syncope

Limb and skin

›Local symptoms

›Focal erythema

›Skin breakdown

›Wound drainage

›New rash

Neurologic and vascular

›Limb threat symptoms

›Numbness

›Weakness

›Cold limb

›New claudication

Genitourinary and pregnancy

›Pregnancy related

›Pregnancy possibility

›Postpartum status

06Collateral History and Family History/chafh11

Collateral sources

›Source and reliability

›Family report

›Caregiver report

›Facility report

Family thrombosis history

›Inherited risk clues

›First degree relative VTE under age 50

›Known inherited thrombophilia in family

›Recurrent miscarriages in family history

Household and exposure context

›Context

›Recent sick contacts

›Functional support at home

07Risk Factors/rf27

Thrombosis risk factors

›Virchow triad aligned risks

›Recent immobilization

›Recent hospitalization

›Long distance travel

›Recent surgery

›Major trauma

›Active cancer

›Pregnancy

›Postpartum

›Estrogen exposure

›Prior VTE

›Known thrombophilia

Anatomic and device risks

›Venous flow obstruction risks

›Central venous catheter

›Iliac vein compression concern

›Pelvic mass history

Bleeding risk factors

›Bleeding risk modifiers

›Recent major bleeding

›Severe liver disease

›Severe kidney disease

›Thrombocytopenia history

Special populations

›Population modifiers

›Pregnancy

›Postpartum

08Differential Diagnosis/ddx32

Life threatening

›Cannot miss diagnoses

›Pulmonary embolism (I26.99)

›Phlegmasia cerulea dolens

›Acute limb ischemia (I74.3)

›Necrotizing soft tissue infection (M72.6)

›Compartment syndrome

Common

›Common causes of leg swelling or pain

›Deep vein thrombosis (I82.40)

›Cellulitis (L03.11)

›Superficial thrombophlebitis (I80.0)

›Ruptured Baker cyst

›Muscle strain or hematoma

›Chronic venous insufficiency (I87.2)

Less common

›Less common causes

›Lymphedema (I89.0)

›Heart failure related edema (I50.9)

›Nephrotic syndrome

›Hypoalbuminemia

›Popliteal artery aneurysm

Mimics and distinguishing clues

›Key distinguishing features

›Cellulitis

›Fever

›Diffuse erythema with skin tenderness

›Baker cyst rupture

09Past Medical History/pmh17

Thromboembolic history

›Prior VTE

›Prior DVT episodes

›Prior PE episodes

›Provoked versus unprovoked history

Cancer and systemic disease

›Prothrombotic conditions

›Active malignancy

›Inflammatory bowel disease

›Nephrotic syndrome

›Myeloproliferative disorders

Bleeding history

›Bleeding risk history

›Prior gastrointestinal bleed

›Prior intracranial hemorrhage

›Prior anticoagulant adverse events

Procedures and devices

›Prior procedures

›Recent orthopedic surgery

›Indwelling venous catheters

›Prior venous stents

10Physical Exam/exam26

General and vitals

›Overall status

›Hemodynamic stability

›Respiratory distress

›Fever

Limb inspection and palpation

›Lower extremity exam

›Unilateral circumference difference

›Pitting edema

›Non pitting edema

›Calf tenderness

›Thigh tenderness

›Erythema and warmth

›Dilated superficial veins

›Skin breakdown

Vascular exam

›Perfusion assessment

›Dorsalis pedis pulse

›Posterior tibial pulse

›Capillary refill

›Limb temperature

Cardiopulmonary exam

›PE screening exam

›Tachycardia

›Tachypnea

›Hypoxemia

›Signs of right heart strain

11Lab Studies/labs16

Core labs for suspected DVT

›Baseline labs for treatment safety

›CBC

›Creatinine and eGFR

›AST and ALT

›PT and INR

›aPTT

D dimer strategy

›D dimer use

›Low pretest probability with negative D dimer supports exclusion

›Moderate to high pretest probability does not exclude with negative D dimer

›Age adjusted threshold local protocol dependent

Pregnancy testing

›Pregnancy status when relevant

›Urine or serum hCG

›Pregnancy modifies imaging choice

Additional labs with PE concern

›If PE concern

›Troponin

›BNP

12Imaging/img25

Scoring Systems

›Pretest probability tools

›Wells score for DVT

›Low probability pathway supports D dimer first local protocol dependent

›Moderate or high probability pathway supports ultrasound first

›LEFt rule for pregnancy

›Left leg symptoms

›Edema with calf circumference difference

›First trimester

MRI

›MR venography considerations

›Suspected iliac or pelvic DVT with nondiagnostic ultrasound

›Pregnancy with suspected iliocaval thrombosis

›Contrast risk considerations

›CT venography considerations

›Suspected pelvic or iliac DVT when ultrasound negative but suspicion remains

›Alternative diagnosis evaluation when needed

›Radiation exposure caution

›Iodinated contrast nephrotoxicity risk

Ultrasound

›Compression ultrasound strategy

›Proximal compression ultrasound

›Whole leg ultrasound local protocol dependent

›Repeat ultrasound in 5 to 7 days if initial negative and high suspicion

›Iliac vein visualization limitations

›Ultrasound interpretation pitfalls

›Distal calf DVT detection variability

13Special Tests/spec7

Bedside and adjunct assessments

›Bedside adjuncts

›Lower extremity POCUS compression exam local credentialing dependent

›Compartment pressure measurement if compartment syndrome concern

›ABI if arterial insufficiency concern

Hypercoagulability testing considerations

›Thrombophilia testing caveats

›Not ED routine for first provoked event

›Acute thrombosis and anticoagulation can confound results

14ECG/ecg6

ECG when PE concern

›Indications

›Dyspnea with suspected PE

›Chest pain with suspected PE

›High risk patterns

›New right heart strain patterns

›New tachyarrhythmia

15Assessment/ax12

Working diagnosis

›Diagnostic framing

›Suspected lower extremity DVT (I82.40)

›DVT excluded by pathway

›Alternative diagnosis favored

Risk stratification

›Pretest probability synthesis

›Clinical score category

›D dimer result integration

›Ultrasound result integration

Complications to evaluate

›Threats and complications

›PE concern escalation

›Phlegmasia concern

›Bleeding risk with anticoagulation

16Plan/plan50

First hour workflow

›Time critical pathway

›If PE alarm features, resuscitation pathway

›If threatened limb concern, vascular surgery emergent

›If hemodynamically stable, proceed with pretest probability based testing

Differential Management

›!Deep Vein Thrombosis (DVT)→›!Cellulitis→›Superficial thrombophlebitis→

Diagnostic sequencing

›Testing sequence

›Low pretest probability plus D dimer first local protocol dependent

›Moderate or high pretest probability ultrasound first

›If ultrasound negative and high suspicion, repeat ultrasound 5 to 7 days or advanced imaging

Anticoagulation initiation

›If confirmed DVT

›Anticoagulation initiation unless contraindicated

›DOAC option local protocol dependent

›Apixaban

›10 mg PO twice daily for 7 days

›Then 5 mg PO twice daily

›Rivaroxaban

›15 mg PO twice daily for 21 days

›Then 20 mg PO daily

›LMWH option

›Enoxaparin 1 mg per kg SC every 12 hours

›Renal adjustment prompt if eGFR under 30

›Warfarin bridge option local protocol dependent

17Disposition/dispo16

Admission criteria

›Inpatient admission indications

›Hemodynamic instability

›Hypoxemia or PE requiring inpatient care

›Phlegmasia concern

›High bleeding risk requiring monitoring

›Severe renal failure limiting outpatient options

›Inadequate outpatient support

Observation pathway

›ED observation considerations

›Pending repeat imaging plan

›High suspicion with initial negative ultrasound

Discharge criteria

›Outpatient management criteria

›Hemodynamic stability

›No PE alarm features

›Anticoagulation access confirmed

›Bleeding risk acceptable

›Follow up arranged within 24 to 72 hours local protocol dependent

18Discharge Instructions/di23

Copy discharge instructions

›Summary

›You were assessed for a blood clot in the leg called deep vein thrombosis

›Your testing today showed

›Your plan is

›Medications

›Take your blood thinner exactly as prescribed

›Do not take NSAIDs unless you were told it is safe

›Seek care if you miss doses and develop new symptoms

›Activity

›Walking is usually safe unless you were told to restrict activity

›Elevate the leg when resting

›Follow up

›Follow up with your clinician within 24 to 72 hours

›If you need repeat ultrasound, return on the scheduled date

›Return to emergency

›New or worsening shortness of breath

›Chest pain

›Coughing blood

›Fainting

›Rapidly worsening leg pain or swelling

›Blue or very pale foot

›Any uncontrolled bleeding

›Severe headache or new neurologic symptoms

19References/r6

Guidelines and key sources

›Evidence based sources

›NICE guideline NG158 venous thromboembolic diseases diagnosis management 2020 updated

›American Society of Hematology guidelines venous thromboembolism diagnosis 2018

›CHEST guideline antithrombotic therapy for VTE disease 2021 update

›Society of Radiologists in Ultrasound consensus criteria for lower extremity venous ultrasound 2018

›Project instructions source

Evidence & Review

Reviewed by SymptomDx Medical Team · Last reviewed February 24, 2026

SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.

Suspected Deep Vein Thrombosis SymptomsAPPROACH

CHEST AND CARDIOVASCULAR · 19 SECTIONS

⚲

419 items

☷ Legend

⚲

Resuscitation and Universal Approaches9▾

Chest and Cardiovascular12▾

Respiratory11▾

Abdominal and Gastrointestinal24▾

Renal and Urinary7▾

Neurologic11▾

Back and Neck8▾

Women's Health, Pregnancy, and GU11▾

Infectious Disease and Fever Syndromes11▾

Allergy and Dermatology7▾

Musculoskeletal and Extremities14▾

Trauma and Wounds14▾

ENT, Eye, Dental10▾

Endocrine, Metabolic, and Abnormal Labs9▾

Toxicology and Behavioral14▾

Pediatrics16▾

Environmental and Exposure4▾

01History/hx72

Presenting symptoms

›Symptom profile

›Unilateral leg swelling

›Unilateral calf or thigh pain

›Limb heaviness

›Erythema

›Warmth

›Dilated superficial veins

›Bilateral symptoms

›Asymptomatic

›Symptom context

›Recent surgery

›Recent trauma

›Recent immobilization

›Recent long travel

›Postpartum

›Active cancer treatment

›Prior venous thromboembolism history

OPQRST

›OPQRST framework

›Onset

›Provocation and palliation

›Quality

›Region and radiation

›Severity

›Timing

Onset

›Timing of onset

02Alarm Features/alarm23

Time critical threats

›Immediate escalation triggers

›Hemodynamic instability

›Hypoxemia

›Syncope with PE concern

›Severe respiratory distress

›Massive leg swelling with severe pain

›Threatened limb concern

Vital sign danger thresholds

›High risk vitals

›Systolic blood pressure under 90 mmHg

›Oxygen saturation under 90 percent on room air

›Marked tachycardia

›Persistent tachypnea

High risk exam findings

›Exam red flags

›Cyanotic painful swollen leg

›Severe pain out of proportion

›Tense compartments

›Absent distal pulses

›Rapidly spreading erythema

High risk historical triggers

›Context red flags

›Recent major surgery within 4 weeks

›Postpartum within 6 weeks

›Active cancer with new swelling

›Known thrombophilia with new symptoms

03Medications/meds21

Medication reconciliation

›Current medications

›Anticoagulants

›Antiplatelets

›Hormonal contraception

›Estrogen therapy

›Testosterone therapy

›Erythropoiesis stimulating agents

Anticoagulant details

›Anticoagulant specifics

›Last dose timing

›Adherence concerns

›Recent interruptions

›Drug interactions

Bleeding risk medication classes

›Concomitant bleeding risk

›NSAIDs

›SSRIs and SNRIs

›Systemic steroids

Contraindications to anticoagulation

›High risk contraindications

›Active major bleeding

›Recent intracranial hemorrhage

›Recent major surgery with uncontrolled bleeding risk

›Severe thrombocytopenia

04Diet/diet10

Intake and hydration

›Recent intake pattern

›Poor oral intake

›Dehydration risk

›Recent vomiting or diarrhea

Substance exposures

›Exposures

›Caffeine and energy drinks

›Alcohol exposure

Diet related comorbid triggers

›Pattern factors

›High salt intake with baseline edema

›Low protein intake with hypoalbuminemia risk

05Review of Systems/ros19

Cardiopulmonary

›PE related symptoms

›Dyspnea

›Pleuritic chest pain

›Cough

›Hemoptysis

›Syncope

Limb and skin

›Local symptoms

›Focal erythema

›Skin breakdown

›Wound drainage

›New rash

Neurologic and vascular

›Limb threat symptoms

›Numbness

›Weakness

›Cold limb

›New claudication

Genitourinary and pregnancy

›Pregnancy related

›Pregnancy possibility

›Postpartum status

06Collateral History and Family History/chafh11

Collateral sources

›Source and reliability

›Family report

›Caregiver report

›Facility report

Family thrombosis history

›Inherited risk clues

›First degree relative VTE under age 50

›Known inherited thrombophilia in family

›Recurrent miscarriages in family history

Household and exposure context

›Context

›Recent sick contacts

›Functional support at home

07Risk Factors/rf27

Thrombosis risk factors

›Virchow triad aligned risks

›Recent immobilization

›Recent hospitalization

›Long distance travel

›Recent surgery

›Major trauma

›Active cancer

›Pregnancy

›Postpartum

›Estrogen exposure

›Prior VTE

›Known thrombophilia

Anatomic and device risks

›Venous flow obstruction risks

›Central venous catheter

›Iliac vein compression concern

›Pelvic mass history

Bleeding risk factors

›Bleeding risk modifiers

›Recent major bleeding

›Severe liver disease

›Severe kidney disease

›Thrombocytopenia history

Special populations

›Population modifiers

›Pregnancy

›Postpartum

08Differential Diagnosis/ddx32

Life threatening

›Cannot miss diagnoses

›Pulmonary embolism (I26.99)

›Phlegmasia cerulea dolens

›Acute limb ischemia (I74.3)

›Necrotizing soft tissue infection (M72.6)

›Compartment syndrome

Common

›Common causes of leg swelling or pain

›Deep vein thrombosis (I82.40)

›Cellulitis (L03.11)

›Superficial thrombophlebitis (I80.0)

›Ruptured Baker cyst

›Muscle strain or hematoma

›Chronic venous insufficiency (I87.2)

Less common

›Less common causes

›Lymphedema (I89.0)

›Heart failure related edema (I50.9)

›Nephrotic syndrome

›Hypoalbuminemia

›Popliteal artery aneurysm

Mimics and distinguishing clues

›Key distinguishing features

›Cellulitis

›Fever

›Diffuse erythema with skin tenderness

›Baker cyst rupture

09Past Medical History/pmh17

Thromboembolic history

›Prior VTE

›Prior DVT episodes

›Prior PE episodes

›Provoked versus unprovoked history

Cancer and systemic disease

›Prothrombotic conditions

›Active malignancy

›Inflammatory bowel disease

›Nephrotic syndrome

›Myeloproliferative disorders

Bleeding history

›Bleeding risk history

›Prior gastrointestinal bleed

›Prior intracranial hemorrhage

›Prior anticoagulant adverse events

Procedures and devices

›Prior procedures

›Recent orthopedic surgery

›Indwelling venous catheters

›Prior venous stents

10Physical Exam/exam26

General and vitals

›Overall status

›Hemodynamic stability

›Respiratory distress

›Fever

Limb inspection and palpation

›Lower extremity exam

›Unilateral circumference difference

›Pitting edema

›Non pitting edema

›Calf tenderness

›Thigh tenderness

›Erythema and warmth

›Dilated superficial veins

›Skin breakdown

Vascular exam

›Perfusion assessment

›Dorsalis pedis pulse

›Posterior tibial pulse

›Capillary refill

›Limb temperature

Cardiopulmonary exam

›PE screening exam

›Tachycardia

›Tachypnea

›Hypoxemia

›Signs of right heart strain

11Lab Studies/labs16

Core labs for suspected DVT

›Baseline labs for treatment safety

›CBC

›Creatinine and eGFR

›AST and ALT

›PT and INR

›aPTT

D dimer strategy

›D dimer use

›Low pretest probability with negative D dimer supports exclusion

›Moderate to high pretest probability does not exclude with negative D dimer

›Age adjusted threshold local protocol dependent

Pregnancy testing

›Pregnancy status when relevant

›Urine or serum hCG

›Pregnancy modifies imaging choice

Additional labs with PE concern

›If PE concern

›Troponin

›BNP

12Imaging/img25

Scoring Systems

›Pretest probability tools

›Wells score for DVT

›Low probability pathway supports D dimer first local protocol dependent

›Moderate or high probability pathway supports ultrasound first

›LEFt rule for pregnancy

›Left leg symptoms

›Edema with calf circumference difference

›First trimester

MRI

›MR venography considerations

›Suspected iliac or pelvic DVT with nondiagnostic ultrasound

›Pregnancy with suspected iliocaval thrombosis

›Contrast risk considerations

›CT venography considerations

›Suspected pelvic or iliac DVT when ultrasound negative but suspicion remains

›Alternative diagnosis evaluation when needed

›Radiation exposure caution

›Iodinated contrast nephrotoxicity risk

Ultrasound

›Compression ultrasound strategy

›Proximal compression ultrasound

›Whole leg ultrasound local protocol dependent

›Repeat ultrasound in 5 to 7 days if initial negative and high suspicion

›Iliac vein visualization limitations

›Ultrasound interpretation pitfalls

›Distal calf DVT detection variability

13Special Tests/spec7

Bedside and adjunct assessments

›Bedside adjuncts

›Lower extremity POCUS compression exam local credentialing dependent

›Compartment pressure measurement if compartment syndrome concern

›ABI if arterial insufficiency concern

Hypercoagulability testing considerations

›Thrombophilia testing caveats

›Not ED routine for first provoked event

›Acute thrombosis and anticoagulation can confound results

14ECG/ecg6

ECG when PE concern

›Indications

›Dyspnea with suspected PE

›Chest pain with suspected PE

›High risk patterns

›New right heart strain patterns

›New tachyarrhythmia

15Assessment/ax12

Working diagnosis

›Diagnostic framing

›Suspected lower extremity DVT (I82.40)

›DVT excluded by pathway

›Alternative diagnosis favored

Risk stratification

›Pretest probability synthesis

›Clinical score category

›D dimer result integration

›Ultrasound result integration

Complications to evaluate

›Threats and complications

›PE concern escalation

›Phlegmasia concern

›Bleeding risk with anticoagulation

16Plan/plan50

First hour workflow

›Time critical pathway

›If PE alarm features, resuscitation pathway

›If threatened limb concern, vascular surgery emergent

›If hemodynamically stable, proceed with pretest probability based testing

Differential Management

›!Deep Vein Thrombosis (DVT)→›!Cellulitis→›Superficial thrombophlebitis→

Diagnostic sequencing

›Testing sequence

›Low pretest probability plus D dimer first local protocol dependent

›Moderate or high pretest probability ultrasound first

›If ultrasound negative and high suspicion, repeat ultrasound 5 to 7 days or advanced imaging

Anticoagulation initiation

›If confirmed DVT

›Anticoagulation initiation unless contraindicated

›DOAC option local protocol dependent

›Apixaban

›10 mg PO twice daily for 7 days

›Then 5 mg PO twice daily

›Rivaroxaban

›15 mg PO twice daily for 21 days

›Then 20 mg PO daily

›LMWH option

›Enoxaparin 1 mg per kg SC every 12 hours

›Renal adjustment prompt if eGFR under 30

›Warfarin bridge option local protocol dependent

17Disposition/dispo16

Admission criteria

›Inpatient admission indications

›Hemodynamic instability

›Hypoxemia or PE requiring inpatient care

›Phlegmasia concern

›High bleeding risk requiring monitoring

›Severe renal failure limiting outpatient options

›Inadequate outpatient support

Observation pathway

›ED observation considerations

›Pending repeat imaging plan

›High suspicion with initial negative ultrasound

Discharge criteria

›Outpatient management criteria

›Hemodynamic stability

›No PE alarm features

›Anticoagulation access confirmed

›Bleeding risk acceptable

›Follow up arranged within 24 to 72 hours local protocol dependent

18Discharge Instructions/di23

Copy discharge instructions

›Summary

›You were assessed for a blood clot in the leg called deep vein thrombosis

›Your testing today showed

›Your plan is

›Medications

›Take your blood thinner exactly as prescribed

›Do not take NSAIDs unless you were told it is safe

›Seek care if you miss doses and develop new symptoms

›Activity

›Walking is usually safe unless you were told to restrict activity

›Elevate the leg when resting

›Follow up

›Follow up with your clinician within 24 to 72 hours

›If you need repeat ultrasound, return on the scheduled date

›Return to emergency

›New or worsening shortness of breath

›Chest pain

›Coughing blood

›Fainting

›Rapidly worsening leg pain or swelling

›Blue or very pale foot

›Any uncontrolled bleeding

›Severe headache or new neurologic symptoms

19References/r6

Guidelines and key sources

›Evidence based sources

›NICE guideline NG158 venous thromboembolic diseases diagnosis management 2020 updated

›American Society of Hematology guidelines venous thromboembolism diagnosis 2018

›CHEST guideline antithrombotic therapy for VTE disease 2021 update

›Society of Radiologists in Ultrasound consensus criteria for lower extremity venous ultrasound 2018

›Project instructions source

Evidence & Review

Reviewed by SymptomDx Medical Team · Last reviewed February 24, 2026

SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.