›Depression comorbidity 24 to 88% in panic disorder
›Critical to screen given suicide risk
›PHQ-2 sensitivity 83%, specificity 92% for major depression
›GAD-7 for generalised anxiety
›Sensitivity 60.6 to 89% for GAD, specificity 82 to 87.6%
›Score >= 10 suggests moderate to severe anxiety
›Useful for ED triage and referral planning
›Panic Disorder Severity Scale
›Used for monitoring treatment response in established panic disorder
›7-item self-report
›Tracks frequency, severity, and impairment
06Diagnostic Tests/dt50
Scoring Systems
›Validated decision tools for panic and differential exclusion
›Wells PE score
›Excludes PE as alternate diagnosis
›Score < 2 with D-dimer negative rules out PE in low-risk patients
›ACEP Level B recommendation for PE risk stratification
›PERC rule (Pulmonary Embolism Rule-out Criteria)
›8 criteria: age < 50, HR < 100, SpO2 >= 95%, no prior DVT or PE, no recent trauma or surgery, no haemoptysis, no exogenous oestrogen, no unilateral leg swelling
›If all 8 met in low pretest probability population, PE excluded without D-dimer
›HEART score
›Guides ACS risk when chest pain is a presenting feature
›Score 0 to 3 low risk; score >= 4 warrants further evaluation
›Panic Disorder Severity Scale
›7-item clinician-rated scale for diagnosis confirmation and monitoring
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