›Supportive measures
›Hydration
›Oral fluids
›Warm fluids for throat comfort
›Irritant avoidance
›Tobacco cessation counseling
›Vaping cessation counseling
›Humidification
›Cool-mist humidifier
›Steam exposure cautions
›Symptom-targeted therapy
›Cough
›Dextromethorphan PO 10-20 mg every 4 hours as needed
›Maximum 120 mg/day
›Avoid with serotonergic combinations
›Dextromethorphan PO 30 mg every 6-8 hours as needed
›Maximum 120 mg/day
›Avoid in young children per local labeling
›Benzonatate PO 100 mg three times daily as needed
›Titrate to 200 mg three times daily as needed
›Maximum 600 mg/day
›Avoid in children < 10 years
›Guaifenesin ER PO 600 mg every 12 hours as needed
›Titrate to 1200 mg every 12 hours as needed
›Maximum 2400 mg/day
›Fever or pain
›Acetaminophen PO 500 mg every 6 hours as needed
›Maximum 3000 mg/day typical outpatient limit
›Lower maximum if liver disease or alcohol use
›Ibuprofen PO 400 mg every 6-8 hours as needed
›Maximum 1200 mg/day OTC dosing
›Avoid in CKD, GI bleed risk, late pregnancy
›Wheeze or bronchospasm
›Albuterol MDI 90 mcg per puff
›2 puffs every 4-6 hours as needed
›Spacer use for technique
›Prefer when wheeze present over routine use
Antibiotics and antivirals
›Etiology-directed therapy
›Uncomplicated acute bronchitis
›No antibiotics
›Stewardship recommendation
›Class I recommendation for avoidance of antibiotics in uncomplicated cases
›Pertussis suspected or confirmed
›Azithromycin PO 500 mg day 1
›250 mg daily days 2-5
›Transmission reduction goal
›Clarithromycin PO 500 mg twice daily for 7 days
›Alternative to azithromycin
›Drug interaction review
›Influenza suspected or confirmed with treatment indication
›Oseltamivir PO 75 mg twice daily for 5 days
›If within treatment window or high-risk
›Renal dose adjustment when indicated
›COVID-19 with antiviral eligibility
›Nirmatrelvir-ritonavir per local protocol
›Drug interaction screening
›Renal and hepatic eligibility
Monitoring and reassessment
›Safety checks
›If bronchodilator used
›Heart rate response
›Tremor or anxiety
›If persistent fever
›Re-evaluation for pneumonia
›Consider repeat exam and imaging