Non pharmacologic measures
›Supportive care bundle
›Calm environment
›Reduce crying triggers
›Single examiner when possible
›Hydration
›Oral fluids for mild cases
›IV fluids if poor intake and significant distress
›Oxygen
›Blow by oxygen for hypoxemia
›Escalation only as tolerated
›Dexamethasone
›Indications
›Any severity of croup
›Spasmodic croup with significant symptoms
›Dosing
›0.15 mg per kg PO single dose
›Maximum 10 mg
›Lower dose supported by trials for many patients
›0.6 mg per kg PO single dose
›Maximum 10 mg
›Common ED standard for simplicity
›Alternate routes
›IM dexamethasone for vomiting or refusal
›Same mg per kg dosing options
›Pain may increase agitation
›IV dexamethasone for established IV access
›Same mg per kg dosing options
›Reserve for severe cases
›Nebulized budesonide
›Indications
›Unable to take oral or IM steroids
›Severe symptoms as adjunct
›Dosing
›2 mg nebulized once
›Clinical effect within hours
›Consider combined with dexamethasone when feasible
›Nebulized epinephrine strategy
›Indications
›Stridor at rest
›Moderate to severe work of breathing
›Racemic epinephrine 2.25 percent
›Dose 0.05 mL per kg nebulized
›Maximum 0.5 mL
›Dilute to total 3 mL with normal saline
›Repeat dosing
›Re dose for recurrent severe symptoms
›Escalate disposition after repeated need
›L epinephrine 1 mg per mL
›Dose 0.5 mL per kg nebulized
›Maximum 5 mL
›Equivalent clinical effect to racemic formulations
›Repeat dosing
›Re dose for recurrent severe symptoms
›Continuous monitoring for severe cases
›Monitoring and adverse effects
›Tachycardia expected
›Usually transient
›Reassess perfusion and distress rather than heart rate alone
›Rebound symptom monitoring requirement
›Observation period after dose
›Discharge only when stable off effect
Advanced therapies and rescue
›Heliox
›Indications
›Severe obstruction with poor response to standard therapy
›Bridge while preparing for airway management
›Operational constraints
›Requires specialized setup
›Less effective with high oxygen requirement
›Intubation pathway
›Preparation
›Difficult airway setup
›Surgical airway readiness
›Tube selection
›One size smaller than predicted
›Cuffed tube acceptable with careful pressure monitoring
›Post intubation care
›ICU admission
›Etiology evaluation for atypical disease
Evidence tags and guideline alignment
›Evidence summary
›Corticosteroids reduce symptom severity and return visits
›Supported by multiple randomized trials and systematic reviews
›Broad guideline endorsement in pediatric emergency care
›Nebulized epinephrine provides rapid temporary symptom relief
›Benefit within minutes
›Requires observation due to waning effect