Lower-risk and higher-risk stratification criteria
AHA/AAP PALS 2025 Guidelines
Lasa JJ et al. Part 8: Pediatric Advanced Life Support. Pediatrics 2026
CPR compression depth, rate, drug dosing
IO access, defibrillation energy recommendations
Landmark studies and reviews
Kinney HC, Thach BT. The Sudden Infant Death Syndrome. NEJM 2009
Brainstem serotonin deficiency model
Triple risk convergence framework
Medullary raphé and arcuate nucleus pathology
Carlin RF, Moon RY. Risk Factors, Protective Factors, and Current Recommendations. JAMA Pediatrics 2017
Comprehensive risk factor review
Quantified odds ratios for modifiable and nonmodifiable risk
Evidence levels for protective interventions
Tester DJ et al. Cardiac Genetic Predisposition in SIDS. JACC 2018
Channelopathy genetics in SUID cohort
Prevalence of pathogenic cardiac gene variants
Post-mortem genetic testing rationale
Oltman SP et al. Early Newborn Metabolic Patterning and SIDS. JAMA Pediatrics 2024
Newborn metabolic differences in infants who later died of SIDS
Acylcarnitine and amino acid profiles
Potential future biomarker for SIDS risk
Nama N et al. Infant Outcomes After BRUE. JAMA Pediatrics 2026
Diagnostic yield and outcomes data for BRUE
Risk stratification validation
Recurrence and serious diagnosis rates
Darrow HJ, Carman KA, Wheeler V. SIDS: Common Questions and Answers. AFP 2025
Primary care and emergency medicine practical review
Modifiable risk factors and counseling framework
Updated 2025 clinical guidance
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.