›Minimize dose to avoid respiratory depression and delirium
›Thoracic epidural analgesia
›Gold standard for severe flail chest
›Bilateral injury indication
›Significantly reduces mechanical ventilation duration
›Reduces pneumonia and tracheostomy rates
›Placement level
›T4-T6 for midthoracic injuries
›T6-T8 for lower thoracic injuries
›Contraindications
›Coagulopathy INR > 1.5
›Thoracic spine fractures at insertion level
›Hemodynamic instability
›Paravertebral block
›Alternative to epidural when contraindicated
›Coagulopathy relative contraindication less stringent than epidural
›Spine fractures making epidural unsafe
›Continuous catheter technique preferred
›Bupivacaine 0.25% at 4-8 mL per hour
›Duration 3-5 days typical
›Serratus anterior plane block
›Emerging technique feasible in ED
›Ultrasound guided lateral chest approach
›Safe in anticoagulated patients
›Safe in patients with spinal precautions
›SABRE trial 2024 JAMA Surgery evidence
›Coverage lateral chest ribs 2-9
›Bupivacaine 0.25% 20-30 mL
›Liposomal bupivacaine single-shot option for extended duration
›Erector spinae plane block
›Promising safety and ease profile
›Posterior approach T5-T8 level
›Bilateral blocks possible
›Evidence from multiple case series and trials
›Intercostal nerve blocks
›Option when other regional techniques contraindicated
›Liposomal bupivacaine 266 mg total dose divided per rib
›Single injection duration up to 72 hours
›Limitation
›Does not cover posterior rib fractures
›Requires repeated injections for standard bupivacaine
›Supplemental oxygen
›Titrate to SpO2 >= 94%
›Nasal cannula for mild hypoxemia
›Non-rebreather mask for moderate hypoxemia
›High flow nasal cannula
›SpO2 < 92% despite simple mask
›Flow rates 40-60 L per minute with FiO2 titrated
›Non-invasive ventilation CPAP or BiPAP
›Alert cooperative patients with marginal respiratory status
›CPAP 5-10 cmH2O starting point
›BiPAP IPAP 10-16 cmH2O EPAP 5-8 cmH2O
›Combined with regional analgesia for best effect
›Trial 1-2 hours with close monitoring
›Contraindications to NIV
›Inability to protect airway
›Persistent vomiting
›Active hemoptysis
›GCS < 10
›Mechanical ventilation
›Intubation indications
›Respiratory failure with PaO2 < 60 mmHg despite supplemental oxygen
›PaCO2 > 50 mmHg with pH < 7.30 rising trend
›Failure of NIV trial
›Airway protection required
›Do NOT intubate solely for chest wall instability
›Ventilator settings
›Tidal volume 6-8 mL/kg ideal body weight
›PEEP 5-10 cmH2O to recruit contused lung
›FiO2 titrate to SpO2 94-98%
›Pressure support or SIMV as patient weans
›Ventilator weaning
›Daily spontaneous breathing trials when criteria met
›Adequate analgesia mandatory for successful extubation
›Resuscitation strategy
›Initial resuscitation to adequate perfusion
›Isotonic crystalloid 500-1000 mL bolus for hypotension
›Reassess after each bolus
›Target MAP >= 65 mmHg
›Avoid fluid overload
›Unnecessary fluids worsen pulmonary contusion
›Once perfusion adequate restrict additional fluid
›Vasopressors preferred over excessive fluid for hemodynamic support
›Blood product resuscitation
›Massive hemorrhage
›Packed red blood cells plasma platelets 1:1:1 ratio
›Tranexamic acid 1 g IV over 10 minutes within 3 hours of injury
›Second dose 1 g IV over 8 hours
›Target hemoglobin 70-80 g/L
Surgical stabilization of rib fractures
›Indications for SSRF
›Hemodynamically stable patients with flail chest
›WSES-AAST guidelines moderate grade of recommendation
›Anterolateral flail with respiratory failure
›Failing to wean from mechanical ventilator
›Non-intubated with deteriorating respiratory function
›Optimal timing
›Within 48-72 hours of injury preferred
›Strong grade of recommendation WSES-AAST
›If early contraindicated perform within 3-7 days
›Outcomes evidence
›Mortality 4.2% with SSRF versus 10.1% with nonoperative management
›Approximately 4.5 fewer ventilator days
›Lower pneumonia and tracheostomy rates
›Shorter ICU stay
›Operative technique
›Plate and screw fixation most common
›Precontoured titanium plates
›Typically 2-3 fractures fixed per operative session
›3D CT reconstruction for preoperative planning mandatory
›Contraindications to SSRF
›Absolute contraindication
›Hemodynamic instability
›Relative contraindications
›Advanced age with significant cardiopulmonary comorbidities
›Active malignancy
›Severe pulmonary contusion where surgery adds risk
Adjunct and prevention interventions
›Pulmonary toilet
›Incentive spirometry every 1-2 hours when awake
›Target tidal volume trending toward baseline
›Documents respiratory effort
›Chest physiotherapy and percussion
›Nasotracheal suction if unable to clear secretions
›Early mobilization when hemodynamically stable
›Steroids are contraindicated
›Do NOT use steroids in pulmonary contusion or flail chest
›Not beneficial and potentially harmful
›Bronchoscopy
›Tracheobronchial injury suspected
›Persistent air leak after chest tube
›Massive subcutaneous emphysema
›90% sensitivity for tracheobronchial injury