Nonpharmacologic management
›Initial care bundle
›Relative rest for 48 to 72 hours
›Avoid pivoting and cutting
›Maintain gentle motion as tolerated
›Ice protocol
›15 to 20 minutes
›Every 2 to 3 hours in first 48 hours
›Compression
›Elastic wrap
›Avoid excessive tightness
›Elevation
›Above heart level when possible
›Swelling reduction goal
›Bracing and mobility aids
›Hinged knee brace for collateral ligament sprain (Class IIa)
›MCL grade I to II
›Brace for comfort and protection
›Early ROM encouraged
›LCL grade I to II
›Brace protection
›Avoid varus stress
›Knee immobilizer indications
›Suspected extensor mechanism injury
›Severe pain with instability
›Crutches
›Non-weight-bearing for suspected fracture
›Protected weight-bearing for pain-limited gait
›Rehabilitation pathway
›Early range of motion (Class I)
›Avoid prolonged immobilization when stable
›Quadriceps activation emphasis
›Physical therapy referral
›Persistent pain beyond 7 to 10 days
›Instability episodes
›Analgesics and anti-inflammatory therapy
›Acetaminophen oral
›Adults 650 to 1,000 mg every 6 to 8 hours
›Maximum 3,000 mg per day preferred outpatient
›Lower maximum with liver disease
›Pediatrics 15 mg/kg every 6 hours
›Maximum 60 mg/kg per day
›Maximum 3,000 mg per day absolute
›Ibuprofen oral (Class I)
›Adults 400 mg every 6 to 8 hours
›Maximum 1,200 mg per day OTC
›Higher doses per clinician judgment with GI risk review
›Pediatrics 10 mg/kg every 6 to 8 hours
›Maximum 40 mg/kg per day
›Maximum 600 mg per dose
›Naproxen oral alternative
›Adults 250 to 500 mg twice daily
›Avoid with renal disease
›Avoid late pregnancy
›Topical diclofenac
›Localized pain option
›Lower systemic risk than oral NSAIDs
›Avoid on broken skin
›Opioid short course for severe pain (Class IIb)
›Oxycodone oral 2.5 to 5 mg every 6 hours as needed
›Small quantity only
›Avoid co-prescribing sedatives
›Pediatrics and adolescents 0.05 to 0.1 mg/kg every 6 hours as needed
›Maximum 5 mg per dose
›Caregiver counseling required
›GI protection and contraindications
›NSAID cautions
›History of peptic ulcer disease
›Chronic kidney disease
›Anticoagulation
›Proton pump inhibitor consideration
›High GI risk and NSAID needed
›Shared decision-making
›Arthrocentesis
›Diagnostic indications
›Suspected septic arthritis
›Unexplained large effusion
›Therapeutic indications (Class IIa)
›Tense hemarthrosis with severe pain
›Improved exam after decompression
›Technique and safety notes
›Ultrasound guidance when anatomy difficult
›Anticoagulation risk assessment
›Reduction and immobilization
›Patellar dislocation reduction when present (Class I)
›Neurovascular exam pre and post
›Post-reduction radiograph consideration
Escalation and specialty involvement
›Orthopedics or sports medicine referral triggers
›Suspected ACL tear with instability
›Early rehab initiation
›MRI planning when persistent instability
›Locked knee
›Suspected bucket-handle meniscus
›Time-sensitive surgical evaluation
›High-grade collateral injury
›Significant gapping at 0 degrees
›Multiligament injury concern