CRASH-2 Trial: TXA within 3 hours reduces hemorrhage mortality
1 g IV bolus then 1 g IV over 8 hours
Mortality benefit lost after 3-hour window
Peitzman et al: NOM success rates across injury grades at US trauma centers
Croce et al: Nonoperative management of blunt hepatic trauma
Established safety of NOM in high-grade injuries at experienced centers
Kozar et al: Hepatic complications after NOM in Grade IV-V liver injuries
Coding standards
ICD-10 S36.1: Injury of liver and gallbladder
S36.11: Injury of liver, contusion
S36.12: Laceration of liver, unspecified degree
S36.13: Minor laceration of liver (AAST I)
S36.14: Moderate laceration of liver (AAST II-III)
S36.15: Major laceration of liver (AAST IV-V)
SNOMED CT: Laceration of liver (disorder) 19843004
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