Resuscitation for suspected rupture
›Hemorrhage control strategy
›Damage control resuscitation
›Early balanced transfusion
›Packed red blood cells per massive transfusion protocol
›Plasma per massive transfusion protocol
›Platelets per massive transfusion protocol
›Crystalloid minimization
›Small bolus only if no blood immediately available
›Stop crystalloid once blood products running
›Permissive hypotension targets
›Systolic blood pressure 80 to 90 mmHg
›If altered mental status then higher target individualized
›If traumatic brain injury concern then avoid hypotension
›Vasopressor bridge when needed
›Norepinephrine infusion
›Initiate 0.05 microgram per kg per minute
›Titrate every 2 to 5 minutes
›Typical range 0.05 to 0.5 microgram per kg per minute
›Goal
›Maintain minimal perfusion until hemorrhage control
›Avoid hypertension that increases bleeding
›Opioid analgesia
›Fentanyl IV
›25 to 50 microgram bolus
›Repeat every 5 to 10 minutes as needed
›Monitor for hypotension and respiratory depression
›Hydromorphone IV
›0.2 to 0.5 mg bolus
›Repeat every 10 to 15 minutes as needed
›Reduced dose in older adults
›Antiemetic options
›Ondansetron IV
›4 mg dose
›Repeat once if needed
›QT prolongation risk consideration
›Metoclopramide IV
›10 mg dose
›Akathisia risk
›Avoid in bowel obstruction concern
Anticoagulation reversal when emergent surgery likely
›Warfarin reversal
›Four factor prothrombin complex concentrate
›Weight based dosing per institutional protocol
›Higher dose for INR over 4
›Lower dose for INR 2 to 4
›Vitamin K IV
›5 to 10 mg dose
›Slower onset but sustains reversal
›Factor Xa inhibitor reversal
›Andexanet alfa when available
›High dose regimen for recent high dose ingestion per protocol
›Low dose regimen for lower exposure per protocol
›Four factor prothrombin complex concentrate alternative
›50 units per kg commonly used off label
›Thrombosis risk monitoring
Definitive management coordination
›Operative pathway selection
›Endovascular aneurysm repair suitability
›Adequate proximal neck anatomy on CT angiography
›Adequate iliac access vessels
›Open repair indications
›Unfavorable anatomy for EVAR
›Hemodynamic collapse with no endovascular option
›Perioperative adjuncts
›Antibiotic prophylaxis
›Cefazolin IV per surgical protocol
›Alternative for severe beta lactam allergy per protocol
›Temperature management
›Active warming
›Prevent hypothermia related coagulopathy
Medical management for intact AAA and prevention
›Cardiovascular risk reduction
›Smoking cessation
›Nicotine replacement options
›Counseling and follow up plan
›Statin therapy
›High intensity statin for atherosclerotic risk
›LDL reduction target per prevention guidelines
›Blood pressure control
›Antihypertensive adherence
›Avoid severe uncontrolled hypertension
›Surveillance and elective repair thresholds
›Elective repair size thresholds
›Men diameter 5.5 cm or greater
›Women diameter 5.0 cm or greater
›Growth thresholds
›Expansion 0.5 cm or more in 6 months
›Expansion 1.0 cm or more in 12 months