Browse categories and answer follow-up questions to refine your symptom profile.
Immediate priorities
Initial stabilization
Airway protection triggers
Encephalopathy with loss of protective reflexes
Recurrent emesis with aspiration risk
Circulation targets
Mean arterial pressure 65 mmHg or higher
Urine output 0.5 ml/kg/hour or higher
Point-of-care threats
Hypoglycemia
Active gastrointestinal bleeding
Sepsis physiology
Acute liver failure screen
Acute liver failure definition
Coagulopathy with INR 1.5 or higher
Any hepatic encephalopathy
No known cirrhosis
Illness duration under 26 weeks
High-risk features
Encephalopathy
INR 2.0 or higher
Rapidly rising bilirubin
Severe hypoglycemia
Lactate elevation with shock physiology
Suspected acetaminophen toxicity
Early coordination
Hepatology consultation triggers
Acute liver failure criteria
Severe acute hepatitis with INR 1.5 or higher
Suspected autoimmune hepatitis with coagulopathy
Transplant center referral triggers
Acute liver failure criteria
King’s College criteria met
Progressive encephalopathy
Monitoring
Continuous monitoring set
Cardiac monitoring
Pulse oximetry
Neurologic trend
West Haven encephalopathy grade
Serial mental status documentation
Glucose surveillance
Bedside glucose every 1 to 2 hours in acute liver failure
Key concepts
Syndrome framing
Acute hepatitis pattern
Marked aminotransferase elevation
Variable bilirubin elevation
Cholestatic pattern
Predominant alkaline phosphatase elevation
Predominant direct hyperbilirubinemia
Mixed pattern
Combined hepatocellular and cholestatic features
Time-critical pitfalls
Acetaminophen toxicity without reliable history
Low threshold acetaminophen level
Low threshold N-acetylcysteine if timing unclear
Ischemic hepatitis as shock marker
Profound aminotransferase rise with hypotension episode
Lactate elevation and end-organ hypoperfusion
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.