Browse categories and answer follow-up questions to refine your symptom profile.
Immediate threats
Instability screen
Airway risk
Oropharyngeal mucosal sloughing
Stridor
Voice change
Drooling
Breathing risk
Hypoxia
Tachypnea
Suspected pneumonia
Circulatory risk
Hypotension
Shock physiology
Sepsis concern
High-risk phenotype
Epidermal detachment
Detachment with pain out of proportion
Positive Nikolsky sign
Ocular involvement
Photophobia
Vision change
Severe mucosal involvement
Oral intake failure
Urinary retention or dysuria
Escalation triggers
If airway compromise, activate airway team
If shock, resuscitation bay and sepsis pathway
If epidermal detachment, burn unit or ICU consult pathway
If ocular involvement, emergent ophthalmology
Phenotype sorting
Erythema multiforme pattern recognition
Target lesions
Typical target
3 zones
Central dusky area
Middle pale ring
Outer erythematous ring
Distribution
Acral predominance
Symmetric extremities
Mucosal involvement spectrum
EM minor
Skin predominant
Absent or mild mucosal lesions
EM major
Prominent mucositis
Limited epidermal detachment
SJS/TEN differentiation guardrails
Lesion morphology
SJS/TEN
Widespread dusky macules
Atypical targets
Skin tenderness prominent
EM
Raised typical targets
Acral distribution
Detachment thresholds
SJS
Epidermal detachment under 10 percent body surface area
SJS-TEN overlap
10 to 30 percent detachment
TEN
Over 30 percent detachment
Early consult and isolation
Consultation map
Dermatology
Diagnostic confirmation
Biopsy planning
Ophthalmology
Any conjunctivitis or ocular pain
Any vision symptoms
Gynecology or urology
Genital mucosal erosions
Urinary retention
Burn unit or ICU
Epidermal detachment
Significant fluid losses
Infection control
Standard precautions
Droplet precautions if suspected respiratory infection outbreak context
Immediate supportive priorities
Comfort and hydration
Pain control plan
Oral analgesia if tolerating
Parenteral analgesia if oral intake limited
Fluid strategy
Oral rehydration if feasible
IV fluids if dehydration or poor intake
Medication safety actions
Suspected trigger medication discontinuation
New medication within prior 1 to 3 weeks
High-risk culprits
Sulfonamide antibiotics
Anticonvulsants
Allopurinol
NSAIDs
Allergy and adverse reaction documentation
Agent name
Reaction phenotype
Date of onset
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.