Opioid overdose treated with naloxone and monitoring
Safety today
No driving for 24 hours
No alcohol or sedatives for 24 hours
Stay with a responsible adult for the rest of the day
Naloxone
Keep naloxone available
Teach household how to use it
Return to ED now for
Sleepiness that is hard to wake from
Slow breathing
Blue lips or face
Chest pain
Severe shortness of breath
Repeated vomiting
New confusion
Follow up
Primary care within 1 to 3 days
Addiction care referral as offered
Harm reduction
Avoid using alone
Test dose if returning to use
Avoid mixing with alcohol or benzos
Use supervised consumption services where available
References
Clinical guidelines and key sources
Reference set
American Heart Association resuscitation guidance relevant to opioid associated emergencies
Ventilation prioritization in respiratory arrest
ACEP clinical policy and emergency toxicology practice summaries relevant to naloxone use
Titrated reversal strategy framing
Toxicology and poison center consensus recommendations
Naloxone infusion for recurrent respiratory depression
CDC overdose prevention resources
Harm reduction strategies
SNOMED CT concept mapping
Opioid overdose
ICD-10 coding references
T40.0X1A to T40.4X1A opioid poisoning categories
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.