Non-pharmacologic first-line
›Load management and rehab plan
›Relative rest from provoking activity
›Avoid complete immobilization unless rupture suspected
›Cross-training with pain-limited alternatives
›Progressive tendon loading
›Eccentric strengthening for mid-portion tendinopathy
›Heavy slow resistance option for chronic tendinopathy
›Frequency and progression guided by pain response
›Activity modification and biomechanics
›Technique correction
›Footwear or equipment changes
›Ergonomic adjustments for work
›Adjuncts
›Ice for short-term analgesia
›Heat for stiffness pattern if preferred
›Compression and elevation for reactive swelling
›Bracing and supports
›Counterforce brace for lateral epicondylalgia
›Wrist or thumb spica splint for De Quervain
›Heel lift or temporary offloading for Achilles insertion pain
›Patellar strap for patellar tendinopathy symptom relief
Analgesia and anti-inflammatory medications
›Topical NSAIDs
›Diclofenac gel per local formulary dosing
›Lower systemic exposure than oral NSAIDs
›Preferred when localized superficial tendinopathy
›Oral analgesics
›Acetaminophen per weight and hepatic risk
›Suitable when NSAIDs contraindicated
›Oral NSAIDs short course when appropriate
›Lowest effective dose
›Avoid in high GI bleed risk without protection plan
›Avoid in advanced CKD
›Opioids
›Generally avoid for tendinopathy
›Reserve for short-term severe pain with clear functional impairment
›Small quantity with follow-up plan
Injections and procedures
›Corticosteroid injections
›Avoid in Achilles and other high rupture risk tendons
›Increased rupture risk concern from observational data
›Consider specialist-only pathway when contemplated
›Lateral epicondylalgia
›Short-term pain relief possible
›Worse intermediate and long-term outcomes compared with rehab in multiple trials
›Other injectables
›PRP
›Mixed evidence by tendon and chronicity
›Consider after failed structured rehab in specialist pathway
›High volume or sclerosing approaches
›Specialist selection only
›Variable evidence base
›Aspiration
›Adjacent bursitis with significant fluctuant swelling
›Culture and cell count when infection concern
›Compression dressing after aspiration when appropriate
Regional specific protocols
›Achilles tendinopathy
›Rehab emphasis
›Eccentric or heavy slow resistance program
›Avoid stretching in highly reactive acute phase if worsens pain
›Imaging selection
›Ultrasound for tear concern
›MRI for refractory course or surgical planning
›Rotator cuff tendinopathy
›Early motion and scapular stabilization
›Avoid prolonged sling use unless severe pain
›Targeted rotator cuff and periscapular strengthening
›Subacromial pain syndrome considerations
›Night pain and overhead provocation pattern
›Consider ultrasound for tear suspicion
›Lateral epicondylalgia
›Counterforce brace and rehab
›Eccentric wrist extensor strengthening
›Activity modification for gripping
›Injection caution
›Avoid repeated steroid injections due tendon degeneration risk
Evidence levels and guideline framing
›Evidence framing
›Progressive loading rehab supported by multiple randomized trials and clinical practice guidelines for common tendinopathies
›Consider as Class I recommendation based on consistency of benefit and low harm
›Imaging reserved for atypical features or failure of structured rehab
›Consider as Class I recommendation for resource stewardship and low yield in classic cases
›Corticosteroid injection caution for lateral epicondylalgia long-term outcomes
›Consider as Class IIb recommendation for selective short-term relief with informed consent