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Abdominal aortic aneurysm Acute coronary syndrome (NSTEMI)Acute coronary syndrome (STEMI)Acute decompensated heart failure Acute limb ischemia Acute mesenteric ischemia Aortic dissection Aortic stenosis Atrial fibrillation and flutter Bradyarrhythmia and heart block Cardiac arrest Deep vein thrombosis Myocarditis Pericarditis Pulmonary embolism Stable angina Superficial thrombophlebitis Superior vena cava syndrome Supraventricular tachycardia Syncope (cardiogenic)Unstable angina Ventricular tachycardia

Acute bronchitis Acute respiratory failure Aspiration pneumonia Asthma exacerbation Bronchiolitis Community-acquired pneumonia COVID-19 pneumonia COPD exacerbation Croup Croup (laryngotracheobronchitis)Epiglottitis Hemothorax Hospital-acquired pneumonia Pleural effusion Pneumothorax (traumatic)Pulmonary contusion Spontaneous pneumothorax

Bell's palsy Benign paroxysmal positional vertigo Brain abscess Cauda equina syndrome Cervical radiculopathy Concussion (mild traumatic brain injury)Encephalitis Guillain-Barré syndrome Hemorrhagic stroke (intracerebral)Ischemic stroke Lumbar radiculopathy Malignant spinal cord compression Migraine Peripheral neuropathy (acute)Retropharyngeal abscess Schizophrenia (acute exacerbation)Seizure (breakthrough:known epilepsy)Seizure (first-time)Spinal cord injury Status epilepticus Subarachnoid hemorrhage Tension headache Transient ischemic attack Traumatic brain injury (moderate-severe)Vestibular neuritis Viral meningitis

Acute appendicitis Acute cholecystitis Acute diverticulitis Acute pancreatitis Anal fissure Choledocholithiasis and cholangitis Clostridioides difficile colitis Gastritis Gastroenteritis (viral and bacterial)Gastroesophageal reflux disease Incarcerated or strangulated hernia Inflammatory bowel disease flare Large bowel obstruction Lower GI hemorrhage Peptic ulcer disease Perforated viscus Small bowel obstruction Upper GI hemorrhage

Acute prostatitis Acute urinary retention Ectopic pregnancy Epididymitis Orchitis Ovarian torsion Paraphimosis Pelvic inflammatory disease Priapism Pyelonephritis Renal laceration Ruptured ovarian cyst Testicular torsion Tubo-ovarian abscess Urinary tract infection (uncomplicated)Urolithiasis (renal colic)Vaginal bleeding (non-pregnant)

Acute sinusitis Acute tonsillitis Acute upper respiratory infection Animal bite Bacterial meningitis Cellulitis Conjunctivitis (bacterial)Dental abscess Endocarditis Febrile neutropenia Fournier gangrene Hand-foot-mouth disease Hepatitis (acute)Herpes zoster HIV-related illness Human bite Impetigo Infected diabetic foot ulcer Infectious mononucleosis Influenza Necrotizing fasciitis Osteomyelitis Otitis externa Parasitic infection Periorbital cellulitis Peritonsillar abscess Scabies Sepsis Septic arthritis Spontaneous bacterial peritonitis Tick-borne illness (Lyme disease)Tinea infection Tuberculosis Viral exanthem Wound infection

Achilles tendon rupture ACL and mceniscus tear Ankle fracture Ankle sprain Burn Calcaneus fracture Cervical spine fracture Clavicle fracture Dental avulsion Distal radius fracture Drowning Elbow fracture and dislocation Electrical injury Facial bone fracture Facial laceration Femur fracture Fingertip amputation Forearm fracture (radius and ulna)Frostbite Hand:finger laceration Heat exhaustion Heat stroke Hip fracture Humeral shaft fracture Knee dislocation Knee sprain Lightning injury Mandible fracture Metacarpal fracture Metatarsal fracture Muscle strain Nasal fracture Non-accidental trauma Orbital fracture Patella fracture Phalanx fracture (finger)Proximal humerus fracture Pulmonary contusion Rib fracture Rotator cuff tear (acute traumatic)Scalp laceration Scaphoid fracture Shoulder dislocation Skull fracture Splenic laceration Sternal fracture Supracondylar pediatric fracture Tendon laceration (hand:wrist)Thoracic and lumbar spine fracture Tibia:fibula fracture Tibial plateau fracture Toe fracture Traumatic epistaxis Traumatic hyphema

Acetaminophen toxicity Alcohol intoxication Alcohol withdrawal Anticholinergic toxicity Anticoagulant overdose Benzodiazepine overdose Benzodiazepine:sedative overdose Beta-blocker and calcium channel blocker toxicity Carbon monoxide poisoning Caustic ingestion Digoxin toxicity Drug eruption Foreign body ingestion Opioid intoxication Opioid overdose Opioid withdrawal Organophosphate Salicylate toxicity Serotonin syndrome Stimulant intoxication (cocaine, methamphetamine)Tricyclic antidepressant overdose

Acute anxiety Acute psychosis Agitation:behavioral emergency Bipolar disorder Conversion disorder Major depressive episode Neuroleptic malignant syndrome Suicidal ideation and attempt

Acute low back pain (mechanical)Bursitis Cervical radiculopathy Costochondritis Gout (acute)Lumbar radiculopathy Pseudogout Tendinitis

Acute eczema (Eczema acute flare)Allergic contact dermatitis Erythema multiforme Henoch-Schönlein purpura Pressure injury Psoriasis (acute flare)Stevens-Johnson syndrome Toxic epidermal necrolysis Urticaria (acute)

Envenomation (snake, spider, insect)High-altitude illness Hypothermia

Acute chest syndrome Coagulopathy Hyperviscosity syndrome Sickle cell crisis (vaso-occlusive)Symptomatic anemia Thrombocytopenia (severe)Tumor lysis syndrome

Bronchiolitis Croup Emergency delivery Febrile seizure Kawasaki disease Neonatal jaundice Neonatal sepsis Nursemaid's elbow Pediatric fever 0 to 28 days Pediatric fever 29 to 60 days Pediatric fever 61 to 90 days Pyloric stenosis Slipped capital femoral epiphysis Intussusception

Adrenal crisis Diabetic ketoacidosis Hypercalcemia Hyperosmolar hyperglycemic state Hypertensive emergency Hypertensive urgency Hypoglycemia Myasthenia gravis crisis Myxedema coma Severe hyperkalemia Severe hyponatremia Thyroid storm

Acute laryngitis Acute otitis media Acute pharyngitis Cerumen impaction Epistaxis (anterior)Nasal foreign body Otitis externa Tympanic membrane perforation

Acute angle-closure glaucoma Central retinal artery occlusion Chemical eye injury Corneal abrasion Corneal ulcer Globe rupture Ocular foreign body Orbital cellulitis Retinal detachment

Hyperemesis gravidarum Painful vaginal bleeding in pregnancy Placenta previa Placental abruption Preeclampsia:eclampsia Preterm labor Threatened:inevitable:incomplete abortion

Anaphylaxis Angioedema Cannabis-induced hyperemesis

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Clinical Assessment Checklist

Browse categories and answer follow-up questions to refine your symptom profile.

Red flags and immediate escalation

High-risk triage

Hemodynamic instability with rectal bleeding

If syncope, persistent tachycardia, or hypotension, resuscitation pathway

If ongoing large-volume hematochezia, lower GI bleed pathway

Sepsis concern

If fever and perineal pain out of proportion, necrotizing soft tissue infection pathway

If perianal fluctuance with systemic symptoms, abscess drainage pathway

Severe immunocompromise

If neutropenia or advanced immunosuppression, early surgical consult for perianal infection concern

Inability to complete anorectal exam due to pain

If uncontrolled pain or concern for alternative diagnosis, urgent colorectal surgery evaluation

Key stabilization targets

Physiologic targets

Pain control sufficient for limited perianal inspection

Topical anesthetic consideration before exam

Bowel movement goals

Soft stool daily without straining

Hydration

Oral fluids to support stool softening

Time-critical exclusions

Diagnoses not to miss

Perianal abscess

Fluctuance, induration, fever, or night pain

Thrombosed external hemorrhoid

Acute tender perianal mass

Fournier gangrene

Toxic appearance, crepitus, skin discoloration, severe pain out of proportion

Inflammatory bowel disease with perianal disease

Multiple fissures, lateral fissure, fistula, chronic diarrhea, weight loss

Anal cancer

Indurated nonhealing lesion, mass, persistent pain, weight loss, immunosuppression

Medical Disclaimer

SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.

Last Reviewed: January 15, 2026 by SymptomDX Medical Team

SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.

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