›Adult dosing
›600-900 mg IV every 8 hours
›Pediatric dosing
›10 mg/kg/dose IV every 8 hours
›Maximum 900 mg per dose
›Use cases
›Penicillin allergy
›Anaerobic predominance
›Ceftriaxone IV plus metronidazole IV
›Ceftriaxone adult dosing
›2 g IV every 24 hours
›Ceftriaxone pediatric dosing
›50 mg/kg IV every 24 hours
›Maximum 2 g per dose
›Metronidazole adult dosing
›500 mg IV every 8 hours
›Metronidazole pediatric dosing
›10 mg/kg/dose IV every 8 hours
›Maximum 500 mg per dose
›Coverage profile
›Gram-negative respiratory flora
›Anaerobes
›MRSA coverage escalation
›Vancomycin IV
›Adult dosing
›15-20 mg/kg IV every 8-12 hours
›Pediatric dosing
›15 mg/kg/dose IV every 6 hours
›Monitoring
›AUC-guided dosing when available
›Renal function trend
›Linezolid IV or PO
›Adult dosing
›600 mg every 12 hours
›Pediatric dosing
›10 mg/kg/dose every 8 hours
›Use cases
›Vancomycin intolerance
›High MRSA suspicion with renal compromise
›Corticosteroid for airway edema and pain adjunct
›Dexamethasone IV or PO
›Adult dosing
›10 mg once
›Pediatric dosing
›0.6 mg/kg once
›Maximum 10 mg
›Caution
›Do not delay antibiotics or source control
›Analgesia and antipyretics
›Acetaminophen
›Adult dosing
›650-1000 mg every 6 hours as needed
›Pediatric dosing
›15 mg/kg/dose every 6 hours as needed
›Ibuprofen if no contraindication
›Adult dosing
›400-600 mg every 6-8 hours as needed
›Pediatric dosing
›10 mg/kg/dose every 6-8 hours as needed
›Drainage strategy
›Operative drainage considerations
›Large or well-formed abscess
›Airway compromise
›Failure of medical therapy
›Needle aspiration select cases
›Experienced ENT operator
›Controlled airway environment