Browse categories and answer follow-up questions to refine your symptom profile.
Triage and immediate risks
Time-critical priorities
High-risk flags
Fever 38.0 C or higher
Hypoxia
Chest pain
Dyspnea
New cough
Altered mental status
Focal neurologic deficit
Severe headache
Priapism 4 hours or longer
New unilateral limb swelling
Pregnancy
Immunocompromise or asplenia
Immediate actions
Escalate to resuscitation bay for shock or hypoxia
If suspected acute chest syndrome, initiate oxygen and early transfusion pathway
If suspected stroke, activate stroke protocol and urgent exchange transfusion pathway
Monitoring and targets
Monitoring bundle
Vitals and reassessment cadence
Pain reassessment every 15-30 minutes until controlled
Continuous pulse oximetry for hypoxia or chest symptoms
Hemodynamic and respiratory targets
SpO2 92% or higher
Euvolemia
Early analgesia pathway
Analgesia first hour
Door-to-analgesia goal
First parenteral opioid within 30-60 minutes for severe pain
Multimodal plan
Opioid plus NSAID or acetaminophen when not contraindicated
Early complication screen
Complications to rule out early
Acute chest syndrome
New infiltrate on CXR plus fever or respiratory symptoms
Sepsis
Fever plus hypotension or lactate elevation
Stroke
New neurologic deficit
Splenic sequestration
Rapid anemia plus splenomegaly and shock
Aplastic crisis
Severe anemia plus low reticulocyte count
Hyperhemolysis
Falling hemoglobin after transfusion with hemolysis markers
Consultation triggers
Early consult criteria
Hematology
Transfusion decision-making
Refractory pain requiring ICU-level analgesia
Suspected hyperhemolysis
ICU
Escalating oxygen requirement
Hemodynamic instability
Altered mental status
Urology
Priapism 4 hours or longer
Obstetrics
Pregnancy with vaso-occlusive pain or any fetal concerns
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.