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Airway first
Airway risk stratification
Voice change
Hoarseness
Muffled voice
Stridor
Inspiratory
Biphasic
Drooling
Inability to handle secretions
Tripod posture
Tongue and floor-of-mouth swelling
Rapid progression minutes to hours
Inability to protrude tongue
Laryngeal involvement
Sensation of throat tightness
Globus with respiratory symptoms
High risk anatomy involvement
Posterior tongue
Soft palate
Immediate actions and monitoring
Time critical stabilization
Escalate to resuscitation bay for any airway symptoms
Early anesthesia and ENT involvement
Difficult airway cart at bedside
Continuous monitoring
Pulse oximetry
Cardiac monitoring
IV access
2 large bore peripheral lines if severe
Oxygen support
Nasal cannula to nonrebreather by work of breathing
High flow nasal cannula if impending fatigue
Angioedema phenotype triage
Mechanism classification
Histamine mediated
Urticaria
Pruritus
Bronchospasm
Hypotension
Bradykinin mediated
No urticaria
Slower onset hours
Prominent facial, lip, tongue swelling
Abdominal pain episodes
Early airway intervention triggers
Airway intervention decision points
If stridor or progressive voice change, early awake approach
Awake fiberoptic intubation favored when feasible
Ketamine preferred if sedation needed and airway reflexes preserved
If inability to handle secretions, airway control before deterioration
Prepare for surgical airway backup
Cricothyrotomy kit opened at bedside
SymptomDx is an educational tool for medical professionals. It does not replace clinical judgment. Verify all clinical data and drug dosages with authoritative sources.