Wood E, Albarqouni L, Tkachuk S, et al. Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome? The Rational Clinical Examination Systematic Review. JAMA. 2018
Predictive accuracy of clinical findings for severe withdrawal and DT
JAMA 2018; 320(8):825–833
Haber PS. Identification and Treatment of Alcohol Use Disorder. New England Journal of Medicine. 2025
Contemporary review including pharmacotherapy for AUD after withdrawal
Chand PK, Panda U, Mahadevan J, Murthy P. Management of Alcohol Withdrawal Syndrome in Patients With Alcoholic Liver Disease. Journal of Clinical and Experimental Hepatology. 2022
Long D, Long B, Koyfman A. The Emergency Medicine Management of Severe Alcohol Withdrawal. American Journal of Emergency Medicine. 2017
Emergency medicine perspective — benzodiazepine dosing, adjunct therapies
Pubmed PMID: 28188055
Korkmaz SA, Aldemir E, Gulec Oyekcin D. Successful Treatment of Severe Alcohol Withdrawal Delirium With Very High-Dose Diazepam (260–480 mg) Administration. Current Medical Research and Opinion. 2024
Evidence for no-ceiling diazepam dosing in refractory DT
Pubmed PMID: 38300249
Salottolo K, McGuire E, Mains CW, et al. Occurrence, Predictors, and Prognosis of Alcohol Withdrawal Syndrome and Delirium Tremens Following Traumatic Injury. Critical Care Medicine. 2017
OR 6.05 for DT in trauma with baseline CIWA-Ar >= 10
Pubmed PMID: 28266937
Flannery AH, Adkins DA, Cook AM. Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU. Critical Care Medicine. 2016
Seshadri A, Appelbaum R, Carmichael SP, et al. Prevention of Alcohol Withdrawal Syndrome in the Surgical ICU. Trauma Surgery and Acute Care Open. 2022
Surgical ICU protocol — prophylactic and treatment approaches
PMC9680182
Cuculi F, Kobza R, Ehmann T, Erne P. ECG Changes Amongst Patients With Alcohol Withdrawal Seizures and Delirium Tremens. Swiss Medical Weekly. 2006
QTc prolongation in 63% of DT patients — basis for cardiac monitoring requirement
Pubmed PMID: 16633972
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