›Success rate 77 to 84% with single treatment
›Alternative sclerosants
›Tetracycline and bleomycin have been studied with similar efficacy
›Doxycycline preferred due to availability and tolerability profile
›Outcomes and recurrence
›Recurrence rate higher than surgical hydrocelectomy
›Lower complication rate, lower cost, and faster recovery than surgery
›Repeat sclerotherapy may be offered for recurrence
›Indications for surgery
›Symptomatic large hydrocele causing discomfort or functional limitation
›Communicating hydrocele with associated inguinal hernia risk
›Hydrocele not amenable to sclerotherapy due to septation or complexity
›Pediatric communicating hydrocele persisting beyond 12 to 24 months
›Surgical techniques
›Jaboulay eversion procedure
›Tunica vaginalis everted around spermatic cord and sutured posteriorly
›Standard technique for adult hydrocele
›Lord plication technique
›Multiple radial sutures to plicate tunica vaginalis
›Less dissection — preferred when significant adhesions or inflammation
›Excision technique
›Complete excision of tunica vaginalis sac
›Used for recurrent hydrocele or complex anatomy
›Inguinal approach for pediatric communicating hydrocele
›High ligation of processus vaginalis at internal inguinal ring
›Concurrent hernia repair if present
›Recurrence and complications
›Recurrence rate 0.3 to 5% depending on technique
›Overall postoperative complication rate approximately 18%
›Hematoma — most common complication; usually managed conservatively
›Infection, wound dehiscence — rare
›Chronic scrotal pain — reported in a subset of patients
›Office-based minimal-incision fenestration
›Local anesthesia technique for patients unfit for general or regional anesthesia
›Small incision with fenestration of tunica vaginalis
›Suitable for simple hydroceles in carefully selected patients
Treatment of secondary hydrocele causes
›Filarial hydrocele management
›Doxycycline 200 mg PO daily for 6 weeks targeting Wolbachia endosymbiont
›Reduces adult filarial worm viability and VEGF-A mediated lymphangiogenesis
›Clinical improvement demonstrated in multiple studies
›Diethylcarbamazine (DEC) plus albendazole
›DEC 6 mg per kg PO single dose
›Albendazole 400 mg PO single dose
›Mass drug administration regimen per WHO filariasis elimination program
›Ivermectin plus albendazole alternative regimen
›Ivermectin 150 to 200 mcg per kg PO single dose
›Albendazole 400 mg PO single dose
›Preferred in areas with onchocerciasis co-endemicity
›Surgical hydrocelectomy ultimately required in most filarial hydroceles
›Antifilarial therapy does not fully resolve established hydrocele
›Reactive hydrocele secondary to epididymitis
›Treat underlying epididymitis with antibiotics
›Ceftriaxone 500 mg IM single dose plus doxycycline 100 mg PO twice daily for 10 days (sexually transmitted etiology)
›Levofloxacin 500 mg PO daily for 10 days (enteric or older male with low STI risk)
›Hydrocele typically resolves with successful treatment of underlying infection