›Morphine IV 0.1 mg/kg (typical 4-8 mg)
›Allow 10-15 minutes for peak effect
›Midazolam IV 1-2 mg for muscle relaxation and anxiolysis
›Adequate sedation critical for success
›Reduction maneuver
›Sustained gentle pressure on hernia with one hand
›Guide contents through the ring with the other hand
›Success rate approximately 70%
›Post-reduction monitoring
›Immediate CT or observation for peritonitis
›If hernia reduces under anesthesia in OR: diagnostic laparoscopy required to assess bowel viability (WSES Grade 2B)
›Strangulation or perforation suspected
›Piperacillin-tazobactam IV 3.375 g every 6 hours
›Covers gram-negative enteric organisms and anaerobes
›Initiate within 1 hour of septic shock diagnosis
›Alternative if penicillin allergy
›Ciprofloxacin IV 400 mg every 12 hours plus metronidazole IV 500 mg every 8 hours
›Adjust for renal function
›Uncomplicated hernia repair
›No evidence supports routine postoperative antibiotics for uncomplicated repair
›Single preoperative dose of cefazolin 1-2 g IV within 60 minutes of incision
›Contaminated or dirty wound: continue postoperative antibiotics per surgical team
›Timing of surgery
›Early intervention less than 6 hours from onset
›OR 0.1 for bowel resection compared to delayed surgery
›Immediate OR for strangulation regardless of duration
›Open repair
›Preferred if strangulation with bowel resection anticipated
›Contaminated or dirty field from perforation
›Limited laparoscopic expertise available
›Laparoscopic repair (TAPP or TEP)
›Conditionally recommended over open (lower recurrence, shorter LOS) when expertise available (EAST guidelines 2025)
›TAPP: Transabdominal preperitoneal approach
›TEP: Total extraperitoneal approach
›Mesh vs primary tissue repair
›Mesh repair conditionally recommended in clean or clean-contaminated fields
›Lower recurrence rate (OR 0.34 vs primary tissue repair)
›Cochrane 2023 systematic review supports mesh use in emergency repair
›Avoid mesh in contaminated or dirty fields
›Primary tissue repair (Bassini, Shouldice technique) if gross contamination
›Biologic mesh may be considered in contaminated fields
›Bowel viability assessment
›If bowel appears ischemic intraoperatively
›Warm saline irrigation and 5-10 minutes observation for color and peristalsis return
›If no recovery: bowel resection with primary anastomosis
›Hernioscopy or diagnostic laparoscopy if hernia reduces spontaneously under anesthesia
›WSES Grade 2B recommendation
›Assess viability before proceeding to repair
›Mesh fixation
›Penetrating vs non-penetrating fixation
›Cochrane 2026 systematic review: no significant difference in outcomes
›Non-penetrating (glue, self-gripping) reduces chronic pain risk