Comprehensive review of acute ischemic stroke management
Heit JJ et al. Focused Update to Guidelines for Endovascular Therapy for Emergent Large Vessel Occlusion: Basilar Artery Occlusion Patients. J Neurointerv Surg 2024
Class I recommendation for EVT in basilar artery occlusion
Mendelson SJ, Prabhakaran S. Diagnosis and Management of TIA and Acute Ischemic Stroke. JAMA 2021; 325(11):1088–1098
Evidence-based guidance on thrombolysis and secondary prevention
LIS-specific clinical literature
Barbic D et al. Locked-in Syndrome: A Critical and Time-Dependent Diagnosis. CJEM 2012; 14(5):283–287
Emergency medicine approach to LIS recognition and management
Farr E et al. Locked-in Syndrome: Practical Rehabilitation Management. PM&R 2021; 13(12):1418–1427
mRS 0–3: 46% EVT versus 23% medical alone at 90 days
BAOCHE Trial. Basilar Artery Occlusion Chinese Endovascular. NEJM 2022; 387:1373–1384
Superiority of EVT confirmed in 6–24 hour window
Nguyen TN et al. Endovascular Management of Acute Stroke. Lancet 2024; 403:2303–2320
Contemporary evidence synthesis for endovascular approaches
Disorders of consciousness and diagnosis
Laureys S, Owen AM, Schiff ND. Brain Function in Coma, Vegetative State, and Related Disorders. Lancet Neurol 2004; 3(9):537–546
Foundational paper on consciousness classification
Fischer D, Edlow BL. Coma Prognostication After Acute Brain Injury. JAMA Neurol 2024
Updated review on prognostication tools including CRS-R
Nilsen HW et al. Demographic, Medical, and Clinical Characteristics of a Population-Based Sample of Patients With Long-Lasting Locked-in Syndrome. Neurology 2023; 101(3):e268–e279
Casanova E et al. Locked-in Syndrome: Improvement in the Prognosis After an Early Intensive Multidisciplinary Rehabilitation. Arch Phys Med Rehabil 2003; 84(6):862–865
Evidence for early rehabilitation benefit in LIS
Vansteensel MJ et al. Fully Implanted Brain-Computer Interface in a Locked-In Patient with ALS. NEJM 2016; 375:2060–2066
Landmark BCI paper with direct relevance to total LIS communication
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